(Mouse) Suz12 Antibody (Center) [APR32990G]

Product Specifications

Background

Tissue Location: Expressed in embryonic stem cells.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality (Mouse) Suz12 Antibody (Center) [APR32990G].

Synonyms

Polycomb protein Suz12, Suppressor of zeste 12 protein homolog, Suz12, D11Ertd530e, Kiaa0160

Gene Name

Suz12

Gene ID

52615

UniProt

Q80U70

Chromosomal Location

Nucleus. Chromosome. Note=Localizes to the inactive X chromosome in trophoblast stem cells

Applications

Dilution

WB--1:1000

Function

Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems (By similarity) . Genes repressed by the PRC2/EED- EZH2 complex include HOXA7, HOXB6 and HOXC8.

Molecular Weight

83026

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.