FAM168B Antibody (C-term) [APR32968G]
Product Specifications
Background
Tissue Location: Expressed in the brain, within neuronal axonal fibers and associated with myelin sheets (at protein level) . Expression tends to be lower in the brain of Alzheimer disease patients compared to healthy individuals (at protein level)
Synonyms
Myelin-associated neurite-outgrowth inhibitor, Mani, p20, FAM168B, KIAA0280L, MANI
Gene Name
FAM168B
Gene ID
130074
UniProt
A1KXE4
Chromosomal Location
Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:D4AEP3}. Cell membrane {ECO:0000250|UniProtKB:Q80XQ8}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q80XQ8}. Cell projection, axon {ECO:0000250|UniProtKB:Q80XQ8}. Note=Expressed in neuronal cell bodies and axonal fibers. {ECO:0000250|UniProtKB:Q80XQ8}
Applications
WB
Dilution
WB--1:1000
Function
Inhibitor of neuronal axonal outgrowth. Acts as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2. Positive regulator of CDC27.
Molecular Weight
20324
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FAM168B Antibody (C-term) [APR32968G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=130074
Uniprot URL
https://www.uniprot.org/uniprot/A1KXE4
Available Sizes
Curated Selection
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