FAM168B Antibody (C-term) [APR32968G]

Product Specifications

Background

Tissue Location: Expressed in the brain, within neuronal axonal fibers and associated with myelin sheets (at protein level) . Expression tends to be lower in the brain of Alzheimer disease patients compared to healthy individuals (at protein level)

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FAM168B Antibody (C-term) [APR32968G].

Synonyms

Myelin-associated neurite-outgrowth inhibitor, Mani, p20, FAM168B, KIAA0280L, MANI

Gene Name

FAM168B

Gene ID

130074

UniProt

A1KXE4

Chromosomal Location

Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:D4AEP3}. Cell membrane {ECO:0000250|UniProtKB:Q80XQ8}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q80XQ8}. Cell projection, axon {ECO:0000250|UniProtKB:Q80XQ8}. Note=Expressed in neuronal cell bodies and axonal fibers. {ECO:0000250|UniProtKB:Q80XQ8}

Applications

Dilution

WB--1:1000

Function

Inhibitor of neuronal axonal outgrowth. Acts as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2. Positive regulator of CDC27.

Molecular Weight

20324

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.