Ubiquilin 4 Antibody (N-term) [APR32828G]

Product Specifications

Background

Tissue Location: Highly expressed in pancreas, kidney, skeletal muscle, heart and throughout the brain, and at lower levels in placenta, lung and liver.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Ubiquilin 4 Antibody (N-term) [APR32828G].

Synonyms

Ubiquilin-4, Ataxin-1 interacting ubiquitin-like protein, A1Up, Ataxin-1 ubiquitin-like-interacting protein A1U, Connexin43-interacting protein of 75 kDa, CIP75, UBQLN4, C1orf6, CIP75, UBIN

Gene Name

UBQLN4 {ECO:0000303|PubMed:27113755, ECO:0000312|HGNC:HGNC:1237}

Gene ID

56893

UniProt

Q9NRR5

Chromosomal Location

Nucleus. Cytoplasm. Chromosome Endoplasmic reticulum {ECO:0000250|UniProtKB:Q99NB8}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q99NB8}. Cytoplasmic vesicle, autophagosome. Note=Colocalizes with the proteasome, both in nucleus and cytoplasm (PubMed:15280365) . Exported from the nucleus following interaction with DESI1/POST (PubMed:29666234) . In response to DNA damage and phosphorylation at Ser-318 by ATM, localizes to the nucleus and is recruited to sites of DNA damage (PubMed:30612738) .

Applications

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

15280365271137552966623430612738152803652711375530612738306127383061273827113755296662342345920523459205

Molecular Weight

63853

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.