AMOTL2 Antibody (Center) [APR32609G]
Product Specifications
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AMOTL2 Antibody (Center) [APR32609G].
Synonyms
Angiomotin-like protein 2, Leman coiled-coil protein, LCCP, AMOTL2, KIAA0989
Gene Name
AMOTL2
Gene ID
51421
UniProt
Q9Y2J4
Chromosomal Location
Recycling endosome.
Applications
WB
Dilution
WB--1:2000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC.
Molecular Weight
85764
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=51421
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y2J4
Available Sizes
Curated Selection
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