RFK Antibody (N-term) [APR32383G]
Product Specifications
Background
Tissue Location: Detected in brain, placenta and urinary bladder.
Synonyms
Riboflavin kinase, ATP:riboflavin 5'-phosphotransferase, Flavokinase, RFK
Gene Name
RFK
Gene ID
55312
UniProt
Q969G6
Chromosomal Location
Cytoplasm.
Applications
IHC-P, WB, FC
Dilution
IHC-P--1:100~500 WB--1:1000 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Function
Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF- activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase.
Molecular Weight
17623
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RFK Antibody (N-term) [APR32383G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=55312
Uniprot URL
https://www.uniprot.org/uniprot/Q969G6
Available Sizes
Curated Selection
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