CLASP2 Antibody (C-term) [APR32382G]

Product Specifications

Background

Tissue Location: Brain-specific.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CLASP2 Antibody (C-term) [APR32382G].

Synonyms

CLIP-associating protein 2, Cytoplasmic linker-associated protein 2, Protein Orbit homolog 2, hOrbit2, CLASP2, KIAA0627

Gene Name

CLASP2

Gene ID

23122

UniProt

O75122

Chromosomal Location

Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Golgi apparatus {ECO:0000250|UniProtKB:Q8BRT1}. Golgi apparatus, trans-Golgi network. Cell membrane. Cell projection, ruffle membrane. Note=Localizes to microtubule plus ends (PubMed:15631994) . Localizes to centrosomes, kinetochores and the mitotic spindle from prometaphase. Subsequently localizes to the spindle midzone from anaphase and to the midbody from telophase (PubMed:16866869, PubMed:16914514) . In migrating cells localizes to the plus ends of microtubules within the cell body and to the entire microtubule lattice within the lamella. Localizes to the cell cortex and this requires ERC1 and PHLDB2 (PubMed:16824950) . The MEMO1-RHOA- DIAPH1 signaling pathway controls localization of the phosphorylated form to the cell membrane.

Applications

WB, IHC-P

Dilution

WB--1:1000 IHC-P--1:100~500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.