Activin A Receptor Type IC (ACVR1C) Antibody (N-term A48) [APR32375G]
Product Specifications
Background
Tissue Location: Present in pancreas, heart, colon, small intestine, ovary and the hippocampus, medulla oblongata and putamen of the brain Isoform 1, isoform 2, isoform 3 and isoform 4 are all expressed in the placenta throughout pregnancy.
Synonyms
HGNC:18123
Gene Name
HGNC:18123
Gene ID
130399
UniProt
Q8NER5
Chromosomal Location
Membrane; Single- pass type I membrane protein
Applications
WB, IHC-P
Dilution
WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Molecular Weight
54871
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Activin A Receptor Type IC (ACVR1C) Antibody (N-term A48) [APR32375G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=130399
Uniprot URL
https://www.uniprot.org/uniprot/Q8NER5
Available Sizes
Curated Selection
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