HMHA1 Antibody (Center) [APR32359G]
Product Specifications
Background
Tissue Location: Expressed on cells of the hematopoietic lineage. Detected in dendritic cells and epidermal Langerhans cells. Expressed in peripheral blood mononuclear cells, in all leukemia/lymphoma cell lines. Detected also in some solid tumors and tissues such as cancerous and non-cancerous tissue.
Synonyms
Minor histocompatibility protein HA-1, Minor histocompatibility antigen HA-1, mHag HA-1, HMHA1, KIAA0223
Gene Name
HGNC:17102
Gene ID
23526
UniProt
Q92619
Chromosomal Location
Cytoplasm. Cell projection, ruffle membrane
Applications
WB, IHC-P, FC
Dilution
WB--1:1000 IHC-P--1:100~500 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading. However, also contains N-terminally a BAR- domin which is able to play an autoinhibitory effect on this RhoGAP activity.
Molecular Weight
124614
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HMHA1 Antibody (Center) [APR32359G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=23526
Uniprot URL
https://www.uniprot.org/uniprot/Q92619
Available Sizes
Curated Selection
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