SARS virus EnvE Antibody (C-term) [APR32227G]
Product Specifications
Synonyms
Envelope small membrane protein, E protein, sM protein, E, sM
Gene Name
E {ECO:0000255|HAMAP-Rule:MF_04204}
Gene ID
1489671
UniProt
P59637
Chromosomal Location
Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus membrane {ECO:0000255|HAMAP-Rule:MF_04204, ECO:0000269|PubMed:21450821, ECO:0000269|PubMed:24788150}; Single-pass type III membrane protein {ECO:0000255|HAMAP-Rule:MF_04204}. Note=Colocalizes with S in the host endoplasmic reticulum-Golgi intermediate compartment (PubMed:20861307) The cytoplasmic tail functions as a Golgi complex-targeting signal {ECO:0000255|HAMAP-Rule:MF_04204, ECO:0000269|PubMed:20861307, ECO:0000269|PubMed:21450821}
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Function
Plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis (By similarity) . Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.
Molecular Weight
8361
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SARS virus EnvE Antibody (C-term) [APR32227G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1489671
Uniprot URL
https://www.uniprot.org/uniprot/P59637
Available Sizes
Curated Selection
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