SARS virus EnvE Antibody (C-term) [APR32227G]

Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus membrane {ECO:0000255|HAMAP-Rule:MF_04204, ECO:0000269|PubMed:21450821, ECO:0000269|PubMed:24788150}; Single-pass type III membrane protein {ECO:0000255|HAMAP-Rule:MF_04204}. Note=Colocalizes with S in the host endoplasmic reticulum-Golgi intermediate compartment (PubMed:20861307) The cytoplasmic tail functions as a Golgi complex-targeting signal {ECO:0000255|HAMAP-Rule:MF_04204, ECO:0000269|PubMed:20861307, ECO:0000269|PubMed:21450821}

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis (By similarity) . Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SARS virus EnvE Antibody (C-term) [APR32227G].