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Osteoactivin/GPNMB Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

Abbreviation

Osteoactivin

UniProt

Q14956

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human Osteoactivin/GPNMB protein expressed by Mammalian

Target

Glycoprotein nmb like protein; Gpnmb; HGFIN; NMB; Osteoactivin; Transmembrane glycoprotein; Transmembrane glycoprotein HGFIN; Transmembrane glycoprotein NMB; UNQ; PRO; GPNMB; HGFIN; NMB; Glycoprotein nmb; Glycoprotein nmb like protein; Osteoactivin; Transmembrane glycoprotein; Transmembrane glycoprotein HGFIN; Transmembrane glycoprotein NMB; UNQ1725; PRO9925

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Immunology; Cancer

Purification

Antigen Affinity Purification

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000

Buffer

PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

64kDa

Observed Molecular Weight

100-120 kDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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