Osteoactivin/GPNMB Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Abbreviation
Osteoactivin
UniProt
Q14956
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human Osteoactivin/GPNMB protein expressed by Mammalian
Target
Glycoprotein nmb like protein; Gpnmb; HGFIN; NMB; Osteoactivin; Transmembrane glycoprotein; Transmembrane glycoprotein HGFIN; Transmembrane glycoprotein NMB; UNQ; PRO; GPNMB; HGFIN; NMB; Glycoprotein nmb; Glycoprotein nmb like protein; Osteoactivin; Transmembrane glycoprotein; Transmembrane glycoprotein HGFIN; Transmembrane glycoprotein NMB; UNQ1725; PRO9925
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Immunology; Cancer
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
64kDa
Observed Molecular Weight
100-120 kDa
Isotype
IgG
Available Sizes
Documents
Curated Selection
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