CRUM2 Antibody (C-term) [APR32192G]

Product Specifications

Background

Tissue Location: Expressed in glomeruli, podocytes of the glomerular capillary loops, and parietal glomerular epithelial cells in the kidney (at protein level) (PubMed:29473663, PubMed:27942854) . Expressed in retina, fetal eye and brain (PubMed:15851977) . Also expressed in kidney, RPE/choroid, and at low levels in lung, placenta, and heart (PubMed:15851977) .

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CRUM2 Antibody (C-term) [APR32192G].

Synonyms

Protein crumbs homolog 2, Crumbs-like protein 2, CRB2

Gene Name

HGNC:18688

Gene ID

286204

UniProt

Q5IJ48

Chromosomal Location

[Isoform 1]: Apical cell membrane {ECO:0000250|UniProtKB:Q80YA8}; Single-pass type I membrane protein. Cytoplasm {ECO:0000250|UniProtKB:Q80YA8}. Cell junction {ECO:0000250|UniProtKB:Q80YA8}. Note=O-glucosylation is required for localization at the apical plasma membrane (By similarity) . Distributed in a complex anisotropic pattern on apical cell edges: the level of CRB2 on a cell edge is inversely correlated with the level of MYH10/myosin-IIB (By similarity) . {ECO:0000250|UniProtKB:Q80YA8}

Applications

WB, IHC-P

Dilution

WB--1:1000 IHC-P--1:100~500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.