CRUM2 Antibody (C-term) [APR32192G]
Product Specifications
Background
Tissue Location: Expressed in glomeruli, podocytes of the glomerular capillary loops, and parietal glomerular epithelial cells in the kidney (at protein level) (PubMed:29473663, PubMed:27942854) . Expressed in retina, fetal eye and brain (PubMed:15851977) . Also expressed in kidney, RPE/choroid, and at low levels in lung, placenta, and heart (PubMed:15851977) .
Synonyms
Protein crumbs homolog 2, Crumbs-like protein 2, CRB2
Gene Name
HGNC:18688
Gene ID
286204
UniProt
Q5IJ48
Chromosomal Location
[Isoform 1]: Apical cell membrane {ECO:0000250|UniProtKB:Q80YA8}; Single-pass type I membrane protein. Cytoplasm {ECO:0000250|UniProtKB:Q80YA8}. Cell junction {ECO:0000250|UniProtKB:Q80YA8}. Note=O-glucosylation is required for localization at the apical plasma membrane (By similarity) . Distributed in a complex anisotropic pattern on apical cell edges: the level of CRB2 on a cell edge is inversely correlated with the level of MYH10/myosin-IIB (By similarity) . {ECO:0000250|UniProtKB:Q80YA8}
Applications
WB, IHC-P
Dilution
WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
20299451
Molecular Weight
134265
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CRUM2 Antibody (C-term) [APR32192G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=286204
Uniprot URL
https://www.uniprot.org/uniprot/Q5IJ48
Available Sizes
Curated Selection
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