CMPK2 Antibody (Center) [APR32135G]
Product Specifications
Background
Tissue Location: Among all investigated tumors, leukemia cells show the most abundant expression.
Synonyms
UMP-CMP kinase 2, mitochondrial, Nucleoside-diphosphate kinase, CMPK2
Gene Name
CMPK2
Gene ID
129607
UniProt
Q5EBM0
Chromosomal Location
Mitochondrion.
Applications
WB, IHC-P, FC
Dilution
WB--1:1000 IHC-P--1:100~500 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
May participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. Efficacy is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. May be involved in mtDNA depletion caused by long term treatment with ddC or other pyrimidine analogs. Also displays broad nucleoside diphosphate kinase activity.
Molecular Weight
49448
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CMPK2 Antibody (Center) [APR32135G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=129607
Uniprot URL
https://www.uniprot.org/uniprot/Q5EBM0
Available Sizes
Curated Selection
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