Me2-H4 (K20) Antibody [APR32063G]

Product Specifications

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Me2-H4 (K20) Antibody [APR32063G].

Synonyms

Histone H4, HIST1H4A, H4/A, H4FA

Gene Name

H4C1

Gene ID

121504;554313;8294;8359;8360;8361;8362;8363;8364;8365;8366;8367;8368;8370

UniProt

P62805

Chromosomal Location

Nucleus. Chromosome.

Applications

DB, IHC-P, FC, WB

Dilution

WB--1:1000 DB--1:500 IHC-P--1:100~500 FC--1:10~50

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step methylation specific peptide affinity purification.

Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.