What is the catalog number for EBP1 Antibody (C-term) [APR32012G]?

The catalog number for EBP1 Antibody (C-term) [APR32012G] is APR32012G.

What sizes are available for EBP1 Antibody (C-term) [APR32012G]?

EBP1 Antibody (C-term) [APR32012G] is available in the following size(s): 50 µL, 100 µL, 200 µL, 400 µL.

How many pack sizes does EBP1 Antibody (C-term) [APR32012G] come in?

EBP1 Antibody (C-term) [APR32012G] is available in 4 different pack sizes.

Is EBP1 Antibody (C-term) [APR32012G] in stock?

EBP1 Antibody (C-term) [APR32012G] is currently made to order / not held in immediate stock. Contact us for lead time.

EBP1 Antibody (C-term) [APR32012G]

Product Specifications

Background

Tissue Location: Isoform 2 is undetectable whereas isoform 1 is strongly expressed in cancer cells (at protein level) . Isoform 1 and isoform 2 are widely expressed, including heart, brain, lung, pancreas, skeletal muscle, kidney, placenta and liver

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EBP1 Antibody (C-term) [APR32012G].

Synonyms

Proliferation-associated protein 2G4, Cell cycle protein p38-2G4 homolog, hG4-1, ErbB3-binding protein 1, PA2G4, EBP1

Gene Name

PA2G4

Gene ID

5036

UniProt

Q9UQ80

Chromosomal Location

[Isoform 1]: Cytoplasm. Nucleus, nucleolus Note=Translocates to the nucleus upon treatment with HRG Phosphorylation at Ser-361 by PKC/PRKCD regulates its nucleolar localization.

Applications

IHC-P, FC, WB

Dilution

WB--1:1000 IHC-P--1:100~500 FC--1:10~50

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Function

May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG) . Inhibits transcription of some E2F1- regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap- independent translation of specific viral IRESs (internal ribosomal entry site) (By similarity) . Regulates cell proliferation, differentiation, and survival. Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation (By similarity) .