U2AF1 Antibody (Center S70) [APR31998G]
Product Specifications
Synonyms
Splicing factor U2AF 35 kDa subunit, U2 auxiliary factor 35 kDa subunit, U2 small nuclear RNA auxiliary factor 1, U2 snRNP auxiliary factor small subunit, U2AF1, U2AF35, U2AFBP
Gene Name
U2AF1
Gene ID
102724594;7307
UniProt
Q01081
Chromosomal Location
Nucleus. Nucleus speckle
Applications
IHC-P, WB
Dilution
IHC-P--1:100~500 WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.
Molecular Weight
27872
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality U2AF1 Antibody (Center S70) [APR31998G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=102724594;7307
Uniprot URL
https://www.uniprot.org/uniprot/Q01081
Available Sizes
Curated Selection
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