INDO Antibody (C-term) [APR31982G]
Product Specifications
Background
Tissue Location: Expressed in mature dendritic cells located in lymphoid organs (including lymph nodes, spleen, tonsils, Peyers's patches, the gut lamina propria, and the thymic medulla), in some epithelial cells of the female genital tract, as well as in endothelial cells of term placenta and in lung parenchyma (PubMed:25691885) . Weakly or not expressed in most normal tissues, but mostly inducible in most tissues (PubMed:25691885) . Expressed in more than 50% of tumors, either by tumoral, stromal, or endothelial cells (expression in tumor is associated with a worse clinical outcome) (PubMed:18418598) . Not overexpressed in tumor-draining lymph nodes (PubMed:26155395, PubMed:25691885) .
Synonyms
Indoleamine 2,3-dioxygenase 1, IDO-1, Indoleamine-pyrrole 2,3-dioxygenase, IDO1, IDO, INDO
Gene Name
IDO1
Gene ID
3620
UniProt
P14902
Chromosomal Location
Cytoplasm, cytosol {ECO:0000250|UniProtKB:P28776, ECO:0000303|PubMed:25691885}
Applications
WB, IHC-P
Dilution
WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
176711742569188525691885231031272515725514502282256918852569188525691885
Molecular Weight
45326
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality INDO Antibody (C-term) [APR31982G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3620
Uniprot URL
https://www.uniprot.org/uniprot/P14902
Available Sizes
Curated Selection
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