POLDIP3 Antibody (N-term) [APR31911G]

Product Specifications

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality POLDIP3 Antibody (N-term) [APR31911G].

Synonyms

Polymerase delta-interacting protein 3, 46 kDa DNA polymerase delta interaction protein, p46, S6K1 Aly/REF-like target, SKAR, POLDIP3, KIAA1649, PDIP46

Gene Name

POLDIP3

Gene ID

84271

UniProt

Q9BY77

Chromosomal Location

Nucleus. Nucleus speckle. Cytoplasm. Note=Nucleocytoplasmic shuttling protein

Applications

WB, IF, IHC-P

Dilution

IF--1:25 IHC-P--1:100~500 WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by association with the TREX complex.