G2E3 Antibody (Center) [APR31738G]

Product Specifications

Background

Tissue Location: Predominantly expressed in brain, liver, kidney, testes and ovary.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality G2E3 Antibody (Center) [APR31738G].

Synonyms

G2/M phase-specific E3 ubiquitin-protein ligase, 632-, G2E3, KIAA1333

Gene Name

G2E3

Gene ID

55632

UniProt

Q7L622

Chromosomal Location

Nucleus, nucleolus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm. In the nucleus, delocalizes from the nucleolus to the nucleoplasm in response to DNA damage

Applications

Dilution

WB--1:2000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death.