AMOT Antibody (N-term) [APR31708G]

Product Specifications

Background

Tissue Location: Expressed in placenta and skeletal muscle. Found in the endothelial cells of capillaries as well as larger vessels of the placenta.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AMOT Antibody (N-term) [APR31708G].

Synonyms

Angiomotin, AMOT, KIAA1071

Gene Name

AMOT

Gene ID

154796

UniProt

Q4VCS5

Chromosomal Location

Cell junction, tight junction. Note=Localized on the cell surface. May act as a transmembrane protein

Applications

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.