AMOT Antibody (N-term) [APR31708G]
Product Specifications
Background
Tissue Location: Expressed in placenta and skeletal muscle. Found in the endothelial cells of capillaries as well as larger vessels of the placenta.
Synonyms
Angiomotin, AMOT, KIAA1071
Gene Name
AMOT
Gene ID
154796
UniProt
Q4VCS5
Chromosomal Location
Cell junction, tight junction. Note=Localized on the cell surface. May act as a transmembrane protein
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.
Molecular Weight
118085
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AMOT Antibody (N-term) [APR31708G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=154796
Uniprot URL
https://www.uniprot.org/uniprot/Q4VCS5
Available Sizes
Curated Selection
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