ECSCR Antibody (C-term) [APR31612G]

Product Specifications

Background

Tissue Location: Highest expression in endothelial cells. Also detected in vascular smooth muscle, macrophages, lymphocytes, and mast cells.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ECSCR Antibody (C-term) [APR31612G].

Synonyms

Endothelial cell-specific chemotaxis regulator, Apoptosis regulator through modulating IAP expression, ARIA, Endothelial cell-specific molecule 2, ECSCR, ECSM2

Gene Name

ECSCR

Gene ID

641700

UniProt

Q19T08

Chromosomal Location

Cell membrane; Single-pass type I membrane protein. Cytoplasm

Applications

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2.