ECSCR Antibody (C-term) [APR31612G]
Product Specifications
Background
Tissue Location: Highest expression in endothelial cells. Also detected in vascular smooth muscle, macrophages, lymphocytes, and mast cells.
Synonyms
Endothelial cell-specific chemotaxis regulator, Apoptosis regulator through modulating IAP expression, ARIA, Endothelial cell-specific molecule 2, ECSCR, ECSM2
Gene Name
ECSCR
Gene ID
641700
UniProt
Q19T08
Chromosomal Location
Cell membrane; Single-pass type I membrane protein. Cytoplasm
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2.
Molecular Weight
21295
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ECSCR Antibody (C-term) [APR31612G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=641700
Uniprot URL
https://www.uniprot.org/uniprot/Q19T08
Available Sizes
Curated Selection
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