SLC27A1 Antibody (C-term) [APR31548G]
Product Specifications
Background
Tissue Location: Highest levels of expression are detected in muscle and adipose tissue small, intermediate levels in small intestine, and barely detectable in liver. Expressed in brain gray matter (PubMed:21395585) .
Synonyms
Long-chain fatty acid transport protein 1, FATP-1, Fatty acid transport protein 1, 621-, Solute carrier family 27 member 1, SLC27A1, ACSVL5, FATP1
Gene Name
HGNC:10995
Gene ID
376497
UniProt
Q6PCB7
Chromosomal Location
Cell membrane {ECO:0000250|UniProtKB:Q60714}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q60714} Endomembrane system {ECO:0000250|UniProtKB:Q60714}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q60714}. Cytoplasm {ECO:0000250|UniProtKB:Q60714}. Note=Plasma membrane and intracellular membranes, at least in adipocytes. In adipocytes, but not myocytes, insulin via the mTORC1 signaling pathway induces a rapid translocation of SLC27A1 from intracellular compartments to the plasma membrane, paralleled by increased LCFA uptake. Insulin-dependent translocation from the cytoplasm to the cell membrane is regulated by EPRS1 Predominantly cytoplasmic in myocytes. {ECO:0000250|UniProtKB:Q60714}
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
2817823921395585
Molecular Weight
71108
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SLC27A1 Antibody (C-term) [APR31548G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=376497
Uniprot URL
https://www.uniprot.org/uniprot/Q6PCB7
Available Sizes
Curated Selection
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