IL23R Antibody (C-term) [APR31476G]
Product Specifications
Background
Tissue Location: Expressed by monocytes, Th1, Th0, NK and dendritic cells. Isoform 1 is specifically expressed in NK cells
Synonyms
Interleukin-23 receptor, IL-23 receptor, IL-23R, IL23R
Gene Name
IL23R
Gene ID
149233
UniProt
Q5VWK5
Chromosomal Location
Cell membrane; Single-pass type I membrane protein
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
Molecular Weight
71722
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL23R Antibody (C-term) [APR31476G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=149233
Uniprot URL
https://www.uniprot.org/uniprot/Q5VWK5
Available Sizes
Curated Selection
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