PAIP2 Antibody (N-term) [APR31450G]
Product Specifications
Background
Tissue Location: Expressed at highest level in testis, but also abundant in brain, cervix, lung, ovary, placenta, adipose tissue, thymus and thyroid.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PAIP2 Antibody (N-term) [APR31450G].
Synonyms
Polyadenylate-binding protein-interacting protein 2, PABP-interacting protein 2, PAIP-2, Poly (A) -binding protein-interacting protein 2, PAIP2, PAIP2A
Gene Name
PAIP2
Gene ID
51247
UniProt
Q9BPZ3
Chromosomal Location
Cytoplasm.
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Acts as a repressor in the regulation of translation initiation of poly (A) -containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly (A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly (A) RNP structure organization.
Molecular Weight
14984
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=51247
Uniprot URL
https://www.uniprot.org/uniprot/Q9BPZ3
Available Sizes
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