CREB3L4 Antibody (C-term) [APR31445G]
Product Specifications
Background
Tissue Location: According to PubMed:11830526, exclusively expressed in the prostate. Expressed in breast and prostate cancer cell lines Expressed in prostatic luminal epithelial cells (at protein level) Expression is significantly more abundant in prostate cancer than in benign prostatic tissue (prostatic hyperplasia) . According to PubMed:12111373, also expressed in brain, pancreas and skeletal muscle, and at lower levels in small intestine, testis, leukocyte and thymus
Synonyms
Cyclic AMP-responsive element-binding protein 3-like protein 4, cAMP-responsive element-binding protein 3-like protein 4, Androgen-induced basic leucine zipper protein, AIbZIP, Attaching to CRE-like 1, ATCE1, Cyclic AMP-responsive element-binding protein 4, CREB-4, cAMP-responsive element-binding protein 4, Transcript induced in spermiogenesis protein 40, Tisp40, hJAL, Processed cyclic AMP-responsive element-binding protein 3-like protein 4, CREB3L4, AIBZIP, CREB4, JAL
Gene Name
CREB3L4
Gene ID
148327
UniProt
Q8TEY5
Chromosomal Location
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single- pass type II membrane protein. Note=May also be located in Golgi apparatus
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements (By similarity) .
Molecular Weight
43432
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CREB3L4 Antibody (C-term) [APR31445G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=148327
Uniprot URL
https://www.uniprot.org/uniprot/Q8TEY5
Available Sizes
Curated Selection
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