FRG1 Antibody (C-term) [APR31440G]
Product Specifications
Background
Tissue Location: Expressed in adult muscle, lymphocytes, fetal brain, muscle, and placenta. Also expressed in the smooth muscle of arteries and veins, the sweat glands and the epidermis
Synonyms
Protein FRG1, FSHD region gene 1 protein, FRG1
Gene Name
FRG1
Gene ID
2483
UniProt
Q14331
Chromosomal Location
Nucleus, Cajal body. Nucleus, nucleolus. Cytoplasm. Cytoplasm, myofibril, sarcomere, Z line. Note=Localization changes during myogenesis from mainly cytoplasmic in undifferentiated myoblasts, to strongly nucleolar in early myotubes and back to cytoplasmic 5 days post-differentiation (PubMed:20970242) . Localized at the Z-line in the sarcomere of matured myotubes 8 days post-differentiation (PubMed:20970242) .
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Binds to mRNA in a sequence-independent manner. May play a role in regulation of pre-mRNA splicing or in the assembly of rRNA into ribosomal subunits. May be involved in mRNA transport. May be involved in epigenetic regulation of muscle differentiation through regulation of activity of the histone-lysine N-methyltransferase KMT5B.
Molecular Weight
29172
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FRG1 Antibody (C-term) [APR31440G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2483
Uniprot URL
https://www.uniprot.org/uniprot/Q14331
Available Sizes
Curated Selection
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