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NKX6-1 Antibody (C-term) [APR31430G]

Product Specifications

Background

Tissue Location: Pancreatic beta cells.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NKX6-1 Antibody (C-term) [APR31430G].

Synonyms

Homeobox protein Nkx-61, Homeobox protein NK-6 homolog A, NKX6-1, NKX6A

Gene Name

NKX6-1

Gene ID

4825

UniProt

P78426

Chromosomal Location

Nucleus.

Applications

WB

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in the development of insulin-producing beta cells in the islets of Langerhans at the secondary transition (By similarity) . Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals (By similarity) .

Molecular Weight

37849

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=4825

Uniprot URL

https://www.uniprot.org/uniprot/P78426

Available Sizes

Frequently Asked Questions

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