SOX18 Antibody (N-term) [APR31364G]
Product Specifications
Background
Tissue Location: Detected in heart, lung, placenta, skeletal muscle, liver, kidney, spleen, prostate, ovary, msosmall intestine and colon
Synonyms
Transcription factor SOX-18, SOX18
Gene Name
SOX18
Gene ID
54345
UniProt
P35713
Chromosomal Location
Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}.
Applications
IF, WB
Dilution
WB--1:1000 IF--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Transcriptional activator that binds to the consensus sequence 5'-AACAAAG-3' in the promoter of target genes and plays an essential role in embryonic cardiovascular development and lymphangiogenesis. Activates transcription of PROX1 and other genes coding for lymphatic endothelial markers. Plays an essential role in triggering the differentiation of lymph vessels, but is not required for the maintenance of differentiated lymphatic endothelial cells. Plays an important role in postnatal angiogenesis, where it is functionally redundant with SOX17. Interaction with MEF2C enhances transcriptional activation. Besides, required for normal hair development.
Molecular Weight
40891
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SOX18 Antibody (N-term) [APR31364G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=54345
Uniprot URL
https://www.uniprot.org/uniprot/P35713
Available Sizes
Curated Selection
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