TLR6 Antibody (C-term) [APR31344G]
Product Specifications
Background
Tissue Location: Detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells
Synonyms
Toll-like receptor 6, CD286, TLR6
Gene Name
TLR6
Gene ID
10333
UniProt
Q9Y2C9
Chromosomal Location
Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, phagosome membrane {ECO:0000250|UniProtKB:Q9EPW9}; Single-pass type I membrane protein. Membrane raft. Golgi apparatus. Note=Upon complex formation with CD36 and TLR4, internalized through dynamin-dependent endocytosis. Does not reside in lipid rafts before stimulation but accumulates increasingly in the raft upon the presence of the microbial ligand. In response to diacylated lipoproteins, TLR2:TLR6 heterodimers are recruited in lipid rafts, this recruitment determine the intracellular targeting to the Golgi apparatus (PubMed:16880211) .
Applications
FC, WB, IHC-P
Dilution
FC--1:10~50 WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
2003758416880211114411071144110720037584
Molecular Weight
91880
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TLR6 Antibody (C-term) [APR31344G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=10333
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y2C9
Available Sizes
Curated Selection
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