E2F3 Antibody (Center) [APR31279G]
Product Specifications
Synonyms
Transcription factor E2F3, E2F-3, E2F3, KIAA0075
Gene Name
E2F3
Gene ID
1871
UniProt
O00716
Chromosomal Location
Nucleus.
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters (By similarity) .
Molecular Weight
49162
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality E2F3 Antibody (Center) [APR31279G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1871
Uniprot URL
https://www.uniprot.org/uniprot/O00716
Available Sizes
Curated Selection
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