CIR Antibody (C-term) [APR31211G]
Product Specifications
Background
Tissue Location: Highly expressed in heart, brain, placenta, liver, skeletal muscle and pancreas.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CIR Antibody (C-term) [APR31211G].
Synonyms
Corepressor interacting with RBPJ 1, CBF1-interacting corepressor, Recepin, CIR1, CIR
Gene Name
CIR1
Gene ID
9541
UniProt
Q86X95
Chromosomal Location
Nucleus speckle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with NEK6 in the centrosome
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity) . Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC) . Required for RBPJ-mediated repression of transcription.
Molecular Weight
52313
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=9541
Uniprot URL
https://www.uniprot.org/uniprot/Q86X95
Available Sizes
Curated Selection
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