NFATC4 Antibody (C-term) [APR31076G]
Product Specifications
Background
Tissue Location: Widely expressed, with high levels in placenta, lung, kidney, testis and ovary (PubMed:18675896) . Weakly expressed in spleen and thymus (PubMed:18675896) . In the hippocampus, expressed in the granular layer of the dentate gyrus, in the pyramidal neurons of CA3 region, and in the hippocampal fissure (PubMed:18675896) . Expressed in the heart (at protein level) (PubMed:12370307)
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NFATC4 Antibody (C-term) [APR31076G].
Synonyms
Nuclear factor of activated T-cells, cytoplasmic 4, NF-ATc4, NFATc4, T-cell transcription factor NFAT3, NF-AT3, NFATC4, NFAT3
Gene Name
NFATC4
Gene ID
4776
UniProt
Q14934
Chromosomal Location
Cytoplasm, cytosol. Nucleus. Note=When hyperphosphorylated, localizes in the cytosol. When intracellular Ca (2+) levels increase, dephosphorylation by calcineurin/PPP3CA leads to translocation into the nucleus (PubMed:11997522, PubMed:18347059) . MAPK7/ERK5 and MTOR regulate NFATC4 nuclear export through phosphorylation at Ser-168 and Ser-170 (PubMed:18347059) .
Applications
IF, WB
Dilution
WB--1:1000 IF--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
7749981115145441199752217875713172132021866820125663301774998118668201183470592566330111997522172132021151454411997522
Molecular Weight
95449
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4776
Uniprot URL
https://www.uniprot.org/uniprot/Q14934
Available Sizes
Frequently Asked Questions
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