ENOX2 Antibody (N-term) [APR31045G]
Product Specifications
Background
Tissue Location: Found in the sera of cancer patients with a wide variety of cancers including breast, prostate, lung and ovarian cancers, leukemias, and lymphomas. Not found in the serum of healthy volunteers or patients with disorders other than cancer. Probably shed into serum by cancer cells. Found on the cell borders of renal, kidney and ovarian carcinomas but not on the borders of surrounding non- cancerous stromal cells
Synonyms
Ecto-NOX disulfide-thiol exchanger 2, APK1 antigen, Cytosolic ovarian carcinoma antigen 1, Tumor-associated hydroquinone oxidase, tNOX, Hydroquinone [NADH] oxidase, 1---, Protein disulfide-thiol oxidoreductase, 1---, ENOX2, COVA1
Gene Name
ENOX2
Gene ID
10495
UniProt
Q16206
Chromosomal Location
Cell membrane. Secreted, extracellular space. Note=Extracellular and plasma membrane-associated
Applications
IHC-P, FC, WB
Dilution
IHC-P--1:100 WB--1:2000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD (P) H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biological clock.
Molecular Weight
70082
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ENOX2 Antibody (N-term) [APR31045G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=10495
Uniprot URL
https://www.uniprot.org/uniprot/Q16206
Available Sizes
Curated Selection
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