DOC2A Antibody (Center) [APR31028G]
Product Specifications
Background
Tissue Location: Predominantly expressed in brain. Also expressed in testis.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DOC2A Antibody (Center) [APR31028G].
Synonyms
Double C2-like domain-containing protein alpha, Doc2, Doc2-alpha, DOC2A
Gene Name
DOC2A
Gene ID
8448
UniProt
Q14183
Chromosomal Location
Lysosome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Cell junction, synapse, synaptosome
Applications
FC, WB, IHC-P
Dilution
FC--1:10~50 WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca (2+) -dependent secretory lysosome exocytosis in mast cells.
Molecular Weight
43959
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=8448
Uniprot URL
https://www.uniprot.org/uniprot/Q14183
Available Sizes
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