XBP1 Antibody (C-term) [APR31018G]
Product Specifications
Background
Tissue Location: Expressed in plasma cells in rheumatoid synovium (PubMed:11460154) . Over-expressed in primary breast cancer and metastatic breast cancer cells (PubMed:25280941) . Isoform 1 and isoform 2 are expressed at higher level in proliferating as compared to confluent quiescent endothelial cells (PubMed:19416856)
Synonyms
X-box-binding protein 1, XBP-1, Tax-responsive element-binding protein 5, XBP1, TREB5, XBP2
Gene Name
HGNC:12801
Gene ID
7494
UniProt
P17861
Chromosomal Location
Endoplasmic reticulum. Note=Colocalizes with ERN1 and KDR in the endoplasmic reticulum in endothelial cells in a vascular endothelial growth factor (VEGF) -dependent manner (PubMed:23529610) [Isoform 2]: Nucleus. Cytoplasm {ECO:0000250|UniProtKB:O35426}. Note=Localizes predominantly in the nucleus. Colocalizes in the nucleus with SIRT1. Translocates into the nucleus in a PIK3R-, ER stress-induced- and/or insulin-dependent manner (By similarity) . {ECO:0000250|UniProtKB:O35426}
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
11460154203489238349596
Molecular Weight
28695
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality XBP1 Antibody (C-term) [APR31018G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7494
Uniprot URL
https://www.uniprot.org/uniprot/P17861
Available Sizes
Curated Selection
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