What is the catalog number for ELF4 Antibody (N-term) [APR31013G]?

The catalog number for ELF4 Antibody (N-term) [APR31013G] is APR31013G.

What sizes are available for ELF4 Antibody (N-term) [APR31013G]?

ELF4 Antibody (N-term) [APR31013G] is available in the following size(s): 50 µL, 100 µL, 200 µL, 400 µL.

How many pack sizes does ELF4 Antibody (N-term) [APR31013G] come in?

ELF4 Antibody (N-term) [APR31013G] is available in 4 different pack sizes.

Is ELF4 Antibody (N-term) [APR31013G] in stock?

ELF4 Antibody (N-term) [APR31013G] is currently made to order / not held in immediate stock. Contact us for lead time.

ELF4 Antibody (N-term) [APR31013G]

Product Specifications

Background

Tissue Location: Abundantly expressed in the placenta and in a variety of myeloid leukemia cell lines. Moderate levels of expression in heart, lung, spleen, thymus, peripheral blood lymphocytes, ovary and colon. Lower levels of expression in Jurkat T-cells and other T-cell lines and no expression in brain.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ELF4 Antibody (N-term) [APR31013G].

Synonyms

ETS-related transcription factor Elf-4, E74-like factor 4, Myeloid Elf-1-like factor, ELF4 {ECO:0000312|EMBL:CAI428821}

Gene Name

ELF4 {ECO:0000312|EMBL:CAI42882.1}

Gene ID

2000

UniProt

Q99607

Chromosomal Location

Nucleus, PML body. Note=Accumulation into PML nuclear bodies is mediated by PML

Applications

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter (By similarity) . Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 (By similarity) . Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway.