WHSC1L1 Antibody (N-term) [APR31012G]

Product Specifications

Background

Tissue Location: Highly expressed in brain, heart and skeletal muscle. Expressed at lower level in liver and lung

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality WHSC1L1 Antibody (N-term) [APR31012G].

Synonyms

Histone-lysine N-methyltransferase NSD3, Nuclear SET domain-containing protein 3, Protein whistle, WHSC1-like 1 isoform 9 with methyltransferase activity to lysine, Wolf-Hirschhorn syndrome candidate 1-like protein 1, WHSC1-like protein 1, WHSC1L1, NSD3

Gene Name

HGNC:12767

Gene ID

54904

UniProt

Q9BZ95

Chromosomal Location

Nucleus. Chromosome.

Applications

Dilution

WB--1:2000 WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Function

Histone methyltransferase. Preferentially dimethylates 'Lys- 4' and 'Lys-27' of histone H3 forming H3K2me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression.