TBX6 Antibody (Center) [APR30891G]
Product Specifications
Background
Tissue Location: Expressed in fetal tail bud, posterior spinal tissue, intervertebral disk and testis. Also expressed in adult testis, kidney, lung, muscle and thymus
Synonyms
T-box transcription factor TBX6, T-box protein 6, TBX6
Gene Name
TBX6
Gene ID
6911
UniProt
O95947
Chromosomal Location
Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
Applications
IF, WB
Dilution
IF--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to play also an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity) .
Molecular Weight
47045
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TBX6 Antibody (Center) [APR30891G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6911
Uniprot URL
https://www.uniprot.org/uniprot/O95947
Available Sizes
Curated Selection
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