PURB Antibody (C-term) [APR30888G]
Product Specifications
Background
Tissue Location: Expressed in myocardium of heart failure patients.
Synonyms
Transcriptional activator protein Pur-beta, Purine-rich element-binding protein B, PURB
Gene Name
PURB
Gene ID
5814
UniProt
Q96QR8
Chromosomal Location
Nucleus.
Applications
WB, IF, FC
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Has capacity to bind repeated elements in single-stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine-rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs (By similarity) .
Molecular Weight
33241
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PURB Antibody (C-term) [APR30888G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5814
Uniprot URL
https://www.uniprot.org/uniprot/Q96QR8
Available Sizes
Curated Selection
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