KHSRP Antibody (Center) [APR30828G]
Product Specifications
Background
Tissue Location: Detected in neural and non-neural cell lines.
Synonyms
Far upstream element-binding protein 2, FUSE-binding protein 2, KH type-splicing regulatory protein, KSRP, p75, KHSRP, FUBP2
Gene Name
KHSRP
Gene ID
8570
UniProt
Q92945
Chromosomal Location
Nucleus. Cytoplasm. Note=A small proportion is also found in the cytoplasm of neuronal cell bodies and dendrites.
Applications
IHC-P, IF, WB
Dilution
WB--1:1000 IHC-P--1:100~500 IF--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity) . Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue- specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE) . May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
Molecular Weight
73115
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KHSRP Antibody (Center) [APR30828G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=8570
Uniprot URL
https://www.uniprot.org/uniprot/Q92945
Available Sizes
Curated Selection
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