CACNG8 Antibody (N-term) [APR30815G]
Product Specifications
Background
Tissue Location: Detected in heart left ventricle.
Synonyms
Voltage-dependent calcium channel gamma-8 subunit, Neuronal voltage-gated calcium channel gamma-8 subunit, Transmembrane AMPAR regulatory protein gamma-8, TARP gamma-8, CACNG8, CACNG6
Gene Name
CACNG8
Gene ID
59283
UniProt
Q8WXS5
Chromosomal Location
Cell membrane {ECO:0000250|UniProtKB:Q8VHW2}; Multi-pass membrane protein. Cell junction, synapse, postsynaptic density membrane {ECO:0000250|UniProtKB:Q8VHW2}
Applications
WB, IHC-P
Dilution
WB--1:500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity) . Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs) . Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits.
Molecular Weight
43313
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CACNG8 Antibody (N-term) [APR30815G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=59283
Uniprot URL
https://www.uniprot.org/uniprot/Q8WXS5
Available Sizes
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