CACNG8 Antibody (N-term) [APR30815G]

Product Specifications

Background

Tissue Location: Detected in heart left ventricle.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CACNG8 Antibody (N-term) [APR30815G].

Synonyms

Voltage-dependent calcium channel gamma-8 subunit, Neuronal voltage-gated calcium channel gamma-8 subunit, Transmembrane AMPAR regulatory protein gamma-8, TARP gamma-8, CACNG8, CACNG6

Gene Name

CACNG8

Gene ID

59283

UniProt

Q8WXS5

Chromosomal Location

Cell membrane {ECO:0000250|UniProtKB:Q8VHW2}; Multi-pass membrane protein. Cell junction, synapse, postsynaptic density membrane {ECO:0000250|UniProtKB:Q8VHW2}

Applications

WB, IHC-P

Dilution

WB--1:500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity) . Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs) . Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits.