PHOX2B Antibody (Center) [APR30767G]
Product Specifications
Background
Tissue Location: Expressed in neuroblastoma, brain and adrenal gland
Synonyms
Paired mesoderm homeobox protein 2B, Neuroblastoma Phox, NBPhox, PHOX2B homeodomain protein, Paired-like homeobox 2B, PHOX2B, PMX2B
Gene Name
PHOX2B
Gene ID
8929
UniProt
Q99453
Chromosomal Location
Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Applications
IF, WB
Dilution
IF--1:10~50 WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta- hydrolase and c-fos promoters, and of several enhancers including cAMP- response element and serum-response element.
Molecular Weight
31621
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PHOX2B Antibody (Center) [APR30767G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=8929
Uniprot URL
https://www.uniprot.org/uniprot/Q99453
Available Sizes
Curated Selection
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