BTF3 Antibody (N-term) [APR30728G]
Product Specifications
Synonyms
Transcription factor BTF3, Nascent polypeptide-associated complex subunit beta, NAC-beta, RNA polymerase B transcription factor 3, BTF3, NACB
Gene Name
BTF3
Gene ID
689
UniProt
P20290
Chromosomal Location
Cytoplasm. Nucleus. Note=The heterodimer with NACA is cytoplasmic
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER) . Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription.
Molecular Weight
22168
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BTF3 Antibody (N-term) [APR30728G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=689
Uniprot URL
https://www.uniprot.org/uniprot/P20290
Available Sizes
Curated Selection
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