SORBS1 Antibody (Center) [APR30661G]
Product Specifications
Background
Tissue Location: Detected in skeletal muscle (at protein level) . Widely expressed with highest levels in heart and skeletal muscle
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SORBS1 Antibody (Center) [APR30661G].
Synonyms
HGNC:14565
Gene Name
HGNC:14565
Gene ID
10580
UniProt
Q9BX66
Chromosomal Location
Cell junction, adherens junction. Cell membrane. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Nucleus. Nucleus matrix. Note=Colocalizes with the Ten-1 ICD form of TENM1 in the nucleus (By similarity) . Colocalizes with actin stress fibers. Also detected at the plasma membrane and in neuronal intranuclear inclusions. Colocalized with PXN at focal adhesions during myogenic differentiation.
Applications
WB, IF
Dilution
WB--1:1000 IF--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity) .
Molecular Weight
142513
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=10580
Uniprot URL
https://www.uniprot.org/uniprot/Q9BX66
Available Sizes
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