CPLX3 Antibody (Center) [APR30654G]

Cell junction, synapse {ECO:0000250|UniProtKB:Q8R1B5}. Cell membrane; Lipid-anchor {ECO:0000250|UniProtKB:Q8R1B5}. Note=Enriched at the synaptic terminal (By similarity) . Localized at glycinergic synaptic contacts of AII amacrine cells with OFF cone bipolar cells in the OFF sublamina of the retina inner nuclear layer (By similarity) {ECO:0000250|UniProtKB:Q8R1B5}

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion (By similarity) . Required for the maintenance of synaptic ultrastructure in the adult retina (By similarity) . Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina (By similarity) . Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca (2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca (2+) vesicle release (By similarity) .

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CPLX3 Antibody (Center) [APR30654G].